发明名称 |
Electrocatalytic asymmetric dihydroxylation of olefinic compounds |
摘要 |
A process is disclosed in which optically active glycols are produced through an electrolytic asymmetric dihydroxylation (ADH) reaction involving olefins as substrates. The ADH reaction is mediated by a catalytically active amount of osmium tetroxide or osmium-containing precursor in a protic medium in the presence of chiral ligand. Any lower valent osmium species produced in the course of the ADH reaction is regenerated electrolytically either directly in the absence of a secondary oxidant or indirectly in the presence of a secondary oxidant that itself undergoes electrolytic regeneration.
|
申请公布号 |
US5419817(A) |
申请公布日期 |
1995.05.30 |
申请号 |
US19940182919 |
申请日期 |
1994.01.18 |
申请人 |
SEPRACOR INC. |
发明人 |
GAO, YUN;ZEPP, CHARLES M. |
分类号 |
B01J31/16;B01J31/18;B01J31/40;B01J37/34;C07C29/03;C07C29/48;C07C31/20;C07C31/42;C07C33/18;C07C33/20;C07C33/26;C07C33/30;C07C45/51;C07C49/497;C07C49/82;C07C67/31;C07C69/732;C25B3/02;(IPC1-7):C25B3/02 |
主分类号 |
B01J31/16 |
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
|