发明名称 |
USE OF IGF-BP FOR REFOLDING OF IGF |
摘要 |
The invention relates to the use of Insulin-like growth factor binding protein (IGF-BP) for refolding of Insulin-like growth factor (IGF).The binding protein is preferably any of IGF-BP-1,IGF-BP-2,IGF-BP-3,IGP-BP-4,IGF-BP-5 and IGF-BP-6 and the Insulin-like growth factor is preferably IGF-I. It also relates to the process for the production of biologically active, native IGF-I or IGF-II, characterized in that IGF-I or IGF-II in a reduced or misfolded form is subjected to treatment with IGF-BP.
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申请公布号 |
CA2176599(A1) |
申请公布日期 |
1995.05.26 |
申请号 |
CA19942176599 |
申请日期 |
1994.11.14 |
申请人 |
CHIRON CORPORATION;CHIRON CORP |
发明人 |
NILSSON, BJOERN;HOBER, SOPHIA ELISABETH |
分类号 |
C07K1/00;C07K14/475;C07K14/65;(IPC1-7):C07K14/65 |
主分类号 |
C07K1/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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