发明名称 |
IMMUNOGENIC COMPOSITIONS AGAINST HELICOBACTER INFECTION, POLYPEPTIDES FOR USE IN THE COMPOSITIONS AND NUCLEIC ACID SEQUENCES ENCODING SAID POLYPEPTIDES |
摘要 |
The invention relates to an immunogenic composition, capable of inducing protective antibodies against <u>Helicobacter</u> infection, characterised in that it comprises: i) at least one sub-unit of a urease structural polypeptide from <u>Helicobacter pylori</u>, or a fragment thereof, said fragment being recognised by antibodies reacting with <u>Helicobacter felis</u> urease, and/or at least one sub-unit of a urease structural polypeptide from <u>Helicobacter felis</u>, or a fragment thereof, said fragment being recognised by antibodies reacting with <u>Helicobacter pylori</u> urease; ii) optionally, a urease-associated Heat Shock protein (HSP), or chaperonin, from <u>Helicobacter</u>, or a fragment of said protein. |
申请公布号 |
WO9514093(A1) |
申请公布日期 |
1995.05.26 |
申请号 |
WO1993EP03259 |
申请日期 |
1993.11.19 |
申请人 |
INSTITUT PASTEUR;INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE M |
发明人 |
LABIGNE, AGNES;SUERBAUM, SEBASTIEN;FERRERO, RICHARD |
分类号 |
C12N15/09;A61K38/00;A61K39/00;A61K39/02;A61K39/106;A61K39/39;A61K39/395;A61P1/04;A61P3/02;A61P31/04;A61P35/00;A61P37/02;C07H21/04;C07K14/195;C07K14/205;C07K16/12;C07K16/40;C12N1/15;C12N1/19;C12N1/21;C12N5/10;C12N9/80;C12N15/31;C12P21/02;C12P21/08;C12Q1/68;C12R1/19;G01N33/569;G01N33/574 |
主分类号 |
C12N15/09 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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