发明名称 New preparation process for sulphurated derivatives of imidazole and the new intermediates obtained
摘要 The subject of the invention is a process for the preparation of products of formula (I): <IMAGE> in which: R1 represents alkyl, alkenyl, alkynyl, alkylthio or cycloalkyl R2 and R3 represent in particular hydrogen, halogen, hydroxyl, mercapto, acyl, alkyl, alkenyl, alkoxy, alkylthio, phenyl, benzoyl, phenylthio, amino, carbamoyl, carboxyl, nitro, cyano or -(CH2)m1-S(O)m2-X-R10 with m1 representing 0 to 4 and m2 0 to 2 and X representing a single bond or -NH-, -NH-CO-, -NH-CO-O-, -N=CH-N-R13 or -NH-CO-NH- with R10 and R13 representing hydrogen, alkyl, alkenyl or carbo- or heterocycle, R4 represents in particular -(CH2)m1-S(O)m2-X-R10, -SO2NHCONR14 R15, -SO2NHSO2R14, -SO2NHCOR14, -SO2NHSO2NR14R15 or -SO2NHCO2R14 with R14 and R15 representing in particular hydrogen or alkyl.
申请公布号 AU5300494(A) 申请公布日期 1995.05.25
申请号 AU19940053004 申请日期 1994.01.04
申请人 ROUSSEL UCLAF 发明人 NEERJA BHATNAGAR;JEAN BUENDIA;CHRISTINE GRIFFOUL;HOLGER HEITSCH;ADALBERT WAGNER
分类号 C07D233/66;A61K31/415;A61K31/425;A61K31/44;A61K31/4427;A61K31/443;A61K31/445;A61K31/505;A61P1/00;A61P9/00;A61P9/04;A61P9/12;A61P13/02;A61P13/12;A61P15/00;A61P15/04;A61P43/00;C07C311/08;C07C311/18;C07C311/37;C07C311/51;C07C311/58;C07C311/60;C07C327/58;C07D233/84;C07D233/90;C07D233/92;C07D401/12;C07D403/10;C07D403/12;C07D405/12;C07D417/12 主分类号 C07D233/66
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