| 发明名称 |
IMPROVED INTERFERON POLYMER CONJUGATES |
| 摘要 |
A process is disclosed for preparing long-acting alpha interferon-containing compositions. Alpha interferon is contacted with a relatively small molar excess of a substantially non-antigenic polymer in the presence of a surfactant to preserve bioactivity. Isolation of the desired conjugate species having optimal activity is also disclosed.
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| 申请公布号 |
CA2176229(A1) |
申请公布日期 |
1995.05.18 |
| 申请号 |
CA19942176229 |
申请日期 |
1994.11.10 |
| 申请人 |
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发明人 |
GILBERT, CARL W.;CHO, MYUNG-OK |
| 分类号 |
A61K47/48;A61K38/00;A61K38/21;A61P1/16;A61P5/00;A61P31/12;A61P35/02;A61P37/00;A61P37/02;A61P37/04;A61P37/06;A61P43/00;C07K1/113;C07K14/56;C07K17/08;(IPC1-7):A61K47/48 |
主分类号 |
A61K47/48 |
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