发明名称 |
TIE-2, A NOVEL RECEPTOR TYROSINE KINASE |
摘要 |
The present invention relates to a novel receptor tyrosine kinase, herein referred to as tie-2, to nucleotide sequences and expression vectors encoding tie-2, and to methods of inhibiting tie-2 activity. The invention also relates to other members of the tie-2 receptor tyrosine kinase family. Genetically engineered host cells that express tie-2 may be used to evaluate and screen drugs involved in tie-2 activation and regulation. The invention relates to the use of such drugs as agonists or antagonists of tie-2 activity.
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申请公布号 |
WO9513387(A1) |
申请公布日期 |
1995.05.18 |
申请号 |
WO1994EP03767 |
申请日期 |
1994.11.12 |
申请人 |
MAX-PLANCK-GESELLSCHAFT ZUR FOERDERUNG DER WISSENSC |
发明人 |
RISAU, WERNER |
分类号 |
A61K38/00;C07K14/71;C12N9/12;(IPC1-7):C12N15/63;C07K14/47;C07K14/515;C12N15/62;C12N5/16;C07K16/28 |
主分类号 |
A61K38/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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