发明名称 |
LIPOSOMES: EFFICIENT LOADING AND CONTROLLED RELEASE OF AMPHIPHATIC MOLECULES |
摘要 |
The present invention relates to an improved transmembrane loading procedure for efficient loading of drugs weak amphiphatic and chemicals into liposomes using the transmembrane gradient. The procedure is simple, efficient, safe, economical, and fast. The resulting liposomes loaded with the drug? or chemicals are stable and safe. A storagable form of loadable liposomes has extended period of stability. The procedure is equally applicable for sustained release of liposome-encapsulated drugs. |
申请公布号 |
CA1335565(C) |
申请公布日期 |
1995.05.16 |
申请号 |
CA19890611964 |
申请日期 |
1989.09.19 |
申请人 |
YISSUM RESEARCH AND DEVELOPMENT COMPANY OF THE HEBREW UNIVERSITY OF JERUSALEM AND HADASSAH MEDICAL ORGANIZATION |
发明人 |
BARENHOLZ, YECHEZKEL;HARAN, GILAD |
分类号 |
A61K9/127;A61K49/22;B01J13/02;(IPC1-7):A61K49/00 |
主分类号 |
A61K9/127 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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