| 摘要 |
<p>A process for the production of prefilled syringes free from dangerous residual air or gas bubbles comprising the following steps: the syringe nozzle is temporarily sealed with a suitable removable cap, from the opposite opened end of said syringe at least 80%, preferably 95% or more of the desired volume/dosage solution to be injected is loaded, then the plunger-piston is inserted under vacuum, the syringe is turned, the cap is removed and, through the nozzle, the syringe is completely filled with the remaining quantity of said solution to be injected, the syringe is re-sealed by re-inserting the cap on the tip, optionally under vacuum.</p> |
