摘要 |
1-Biophenylylmethyl-2-oxo-3-aminomethyl-1,2-dihydropyridine derivs. of formula (I) and their salts are new: R1 = H; A; 2-6C alkenyl; or 2-6C alkynyl; R2 = -SO2NH-COOR5; -SO2NH-COR5; etc.;R3 = H; A;etc.;R4 = A-CO-, Ar'-CO-; Ar'-CmH2m-CO-;etc.;R5 = H; 1-6C alkyl opt. contg. O or S in place of 1 CH2 or opt. contg. a C-C double bond and opt. substd. by OH,etc.; A = 1-6C alkyl;Ar' = phenyl opt. mono- or di-substd.,etc.; m= 1-3. |