发明名称 1-aryloxy-3-alkylamino-2-propanol nitrate esters the use thereof and corresponding pharmaceutical composition
摘要 The above nitrate esters, having formula I: <CHEM> the enantiomers and diastereoisomers and the therapeutically acceptable salts thereof, wherein R1 is a chain of general formula II - (-CH2)m - Z - R2, where: m is 1 or 2; Z is an -O- ether, -CONH amide or -COO- ester function; and R2 is a C2-3 straight or branched chain alkyl having at least one nitroxy group as substituent; and Ar is a benzene ring when Z is the ether or ester function, and a naphthalene ring when Z is the amide function, are of use for the treatment of cardiovascular affections.
申请公布号 ZA9405435(B) 申请公布日期 1995.05.11
申请号 ZA19940005435 申请日期 1994.07.22
申请人 PRODESFARMA, S.A. 发明人 MARIA PRAT QUINONES;JOAN PI SALLENT;DAGMAR VEDRILLA VEIT
分类号 A61K31/135;A61K31/165;A61K31/21;A61K31/215;A61P9/08;A61P9/10;C07C217/32;C07C235/34 主分类号 A61K31/135
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