USE OF LOW ANTICOAGULANT HEPARINDERIVATIVES

摘要

The present invention relates to the use of low anticoagulant heparin (LA-heparin), low molecular weight-low anticoagulant heparin (LMW-LA-Heparin) or low anticoagulant heparan sulphate for the manufacture of a medicament regulating phospholipases A2 (PLA2). The medicament can be used against myotoxic phospholipases A2 (PLA2) and against bites from snakes or insects. The medicament also inhibits cellular PLA2 in human leukocytes and can be used for treating tissue damages caused by PLA2 and function as an anti-inflammatory medicament. The medicament can be adapted for injectable, topical or oral administration.