Oasomycin derivatives having antimicrobial action, a process for their preparation, and their use

摘要

The invention relates to macrolactones, which are derivatives of the natural oasomycins A and B, in particular of the formula I <IMAGE> in which R<1> is hydrogen or alpha -mannosyl and R<2> is a radical of the formula (II) <IMAGE> where R<3> is a single or branched alkyl radical optionally itself carrying functional groups and having 1 to 22 C atoms and R<4> is hydrogen, or R<3> and R<4> are single or branched alkyl radicals optionally themselves carrying functional groups and having 1 to 22 C atoms, which can be identical or different and a constituent of a saturated cycloaliphatic or heterocycloaliphatic system, and in particular to macrolactones of the formula (III) <IMAGE> in which R<1> is hydrogen or alpha -mannosyl and R<2> has the meaning indicated. The invention further relates to a process for the preparation of these compounds and to their use as pharmacological active compounds.