发明名称 |
Measuring non-dystrophin proteins and diagnosing muscular dystrophy |
摘要 |
The invention pertains to the dystrophin-glycoprotein complex of mammalian skeletal muscle and a method of isolating said complex. The components of the complex and methods of separating and isolating said components also pertain to the invention. In addition, the invention further relates to a method of diagnosing muscular dystrophy by detecting and quantifying the loss of a non-dystrophin component of the dystrophin-glycoprotein complex with said loss being indicative of muscular dystrophy.
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申请公布号 |
US5413910(A) |
申请公布日期 |
1995.05.09 |
申请号 |
US19920958015 |
申请日期 |
1992.10.07 |
申请人 |
UNIVERSITY OF IOWA RESEARCH FOUNDATION |
发明人 |
CAMPBELL, KEVIN P.;ERVASTI, JAMES M.;OHLENDIECK, KAY;GAVER, MITCHELL G.;KAHL, STEVEN D. |
分类号 |
A61K39/395;A61K38/00;A61K39/00;C07K1/22;C07K14/00;C07K14/47;C07K14/705;C07K16/00;C07K16/18;C07K16/28;C07K19/00;C12P21/08;G01N33/53;G01N33/68;(IPC1-7):G01N33/567 |
主分类号 |
A61K39/395 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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