| 摘要 |
A process for the preparation of a 4-methylpyrimidine of the general formula I <IMAGE> (I) in which R1 denotes C1-C20 alkyl, C3-C8 cycloalkyl, aryl, C7-C12 phenalkyl, C7-C12 alkylphenyl, NH2, NHCN, OH, and SH, in which a 1-aminovinyl methyl ketone of the general formula II <IMAGE> (II) in which R2 and R3 denote C1-C20alkyl, C3-C8 cycloalkyl, aryl, C7-C12 phenylalkyl, C7-C12 alkylphenyl, C1-C20 hydroxyalkyl or together denote a C2-C7 alkylene chain optionally mono- to tetra-substituted by C1-C4 alkyl and optionally interrupted by oxygen, nitrogen, or sulfur, is caused to react with a carboxamide or amidine or a salt thereof of the general formula III <IMAGE> (III) in which R1 has the aforementioned meanings and x stands for oxygen or NH, at temperatures ranging from 20 DEG to 200 DEG C. and pressures ranging from 0.01 to 50 bar.
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