发明名称 |
Process for preparing bovine pericard materials and use thereof |
摘要 |
A process for treating bovine pericard tissue to increase resistance to biological degradation by wet-chemical processing, The wet-chemical processing consists essentially of: (i) separating any adherent fat and basal membrane from the tissue; (ii) contacting the tissue with an aqueous, alkaline solution of sodium hydroxide, potassium hydroxide, lithium hydroxide or sodium carbonate to swell the tissue; (iii) contacting the swollen tissue with an aqueous sodium chloride solution to control the swelling; (iv) contacting the tissue with a solution of a metal-ion complexing agent with a pH in excess of 11; and (v) contacting the tissue with an aqueous buffer solution having a pH of 4.5 to 6.0. Each of steps (ii)-(v) is followed by a water rinse. The pericard tissue is then dried and sterilized.
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申请公布号 |
US5413798(A) |
申请公布日期 |
1995.05.09 |
申请号 |
US19940223826 |
申请日期 |
1994.04.06 |
申请人 |
B. BRAUN MELSUNGEN AKTIENGESELLSCHAFT |
发明人 |
SCHOLL, EDMUND;WALDERT, HELMUT;BEYER, HELMUT |
分类号 |
A61L27/00;A61L27/36;(IPC1-7):A61K33/14;A61K38/17;A61F2/28 |
主分类号 |
A61L27/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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