发明名称 |
PROCESS FOR THE PREPARATION OF RUFLOXACIN AND SALTS THEREOF |
摘要 |
Rufloxacin is prepared by reducing a quinolon disulfide of formula (II) subjecting the 2-mercaptoethyl quinolone thus obtained of formula (III) to a cyclization in a basic medium and hydrolyzing the rufloxacin ester thus obtained to isolate rufloxacin. A new method for hydrolyzing rufloxacin ester to rufloxacin and its pharmaceutically acceptable salts is also described.
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申请公布号 |
WO9511907(A1) |
申请公布日期 |
1995.05.04 |
申请号 |
WO1994EP03512 |
申请日期 |
1994.10.26 |
申请人 |
ARCHIMICA S.P.A.;BELLANI, PIETRO |
发明人 |
BELLANI, PIETRO |
分类号 |
C07D215/56;C07D513/06;(IPC1-7):C07D513/06 |
主分类号 |
C07D215/56 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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