摘要 |
Compounds of general formula (I), wherein R1 is n-propyl or cyclobutyl; R2 is isopropyl, tertiary butyl, cyclobutyl, cyclopentyl or cyclohexyl; R3 is hydrogen; R4 is hydrogen or methyl; as (R)-enantiomer and in the form of free base or pharmaceutically acceptable salts thereof, process for their preparation, pharmaceutical composition, use of and method of treatment of disorders in CNS.
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申请人 |
ASTRA AKTIEBOLAG;EVENDEN, JOHN, LESLIE;HAMMARBERG, EVA, MARIA;HANSSON, HANS, SVERKER;HELLBERG, SVEN, ERIK;JOHANSSON, LARS, GEORGE;LUNDKVIST, JOHAN, RUNE, MICHAEL;ROSS, SVANTE, BERTIL;SOHN, DANIEL, DUNGAN;THORBERG, SETH, OLOV |
发明人 |
EVENDEN, JOHN, LESLIE;HAMMARBERG, EVA, MARIA;HANSSON, HANS, SVERKER;HELLBERG, SVEN, ERIK;JOHANSSON, LARS, GEORGE;LUNDKVIST, JOHAN, RUNE, MICHAEL;ROSS, SVANTE, BERTIL;SOHN, DANIEL, DUNGAN;THORBERG, SETH, OLOV |