发明名称 |
PYRIMIDINE NUCLEOSIDE DERIVATIVE. |
摘要 |
A novel pyrimidine nucleoside derivative of formula (1) or (2) and a salt thereof, wherein R<1> represents amino which may be substituted with hydroxy or acyl; R<2> represents hydrogen or C<5> to C<8> alkyl; R<3> represents hydrogen or hydroxy; and R4 and R5 represent each hydrogen or they may be combined together to represent -R6R<6'>Si-O-SiR7R<7'>-, wherein R6, R<6'>, R7 and R<7'> each represents lower alkyl. This compound has an excellent antitumor effect or serves as a useful intermediate for the synthesis of antitumor drugs. <CHEM> |
申请公布号 |
EP0535231(B1) |
申请公布日期 |
1995.05.03 |
申请号 |
EP19910911192 |
申请日期 |
1991.06.13 |
申请人 |
SANKYO COMPANY LIMITED |
发明人 |
MATSUDA, AKIRA, 10-501, MINAMISHINKAWA;SASAKI, TAKUMA;UEDA, TOHRU |
分类号 |
A61K31/505;A61K31/70;A61K31/7042;A61K31/7052;A61K31/7064;A61K31/7068;A61K31/7072;A61K31/7135;A61P35/00;C07D405/04;C07F7/18;C07H19/06;C07H19/067;C07H19/16;C07H23/00 |
主分类号 |
A61K31/505 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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