发明名称 Preparation process of naphthoquinone derivative and intermediate for the preparation thereof
摘要 Disclosed herein are a naphthoquinone derivative represented by the following formula: <IMAGE> (II) wherein R1 means a hydrogen atom or methyl group, R2 is a hydrogen atom or methyl group, n stands for 0 or an integer of 1-9, and a linkage is a single bond or double bond with the proviso that if n is an integer of 2-9, the linkages may be identical with or different optionally from each other, such as a vitamin K derivative; and a process for producing the naphthoquinone derivative at a high yield without forming any geometric isomer; as well as 1,4,4a,5,8,9a-hexahydro-4a alpha -alkenyl-1 alpha ,4 alpha -methanoanthraquinone derivatives and 1,4,4a,5,8,9a-hexahydro-1 alpha ,4 alpha -methanoanthraquinone derivatives which are useful as intermediates for the preparation of the naphthoquinone derivatives.
申请公布号 US5412124(A) 申请公布日期 1995.05.02
申请号 US19940280550 申请日期 1994.07.26
申请人 EISAI CHEMICAL CO., LTD. 发明人 HAMAMURA, KIMIO;SEKI, CHIAKI;KONISHI, MASAYUKI
分类号 C07C46/00;C07C49/617;C07C49/653;C07C50/10;C07C50/14;(IPC1-7):C07C50/00 主分类号 C07C46/00
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