发明名称 |
Novel (R)-5-carbamoyl-8-fluoro-3-N,N-disubstituted-amino-3,4-dihydro-2H-1-benzopyrans |
摘要 |
3-amino-5-carbamoylchromans and 8-fluoro-3-amino-5-carbamoylchromans, as well as enantiomers and salts thereof, are disclosed. Pharmaceutical compositions containing the compounds as active ingredients are also disclosed. The compounds are useful in the treatment of 5-hydroxytryptamine-mediated disorders of the central nervous system. |
申请公布号 |
ZA9408353(B) |
申请公布日期 |
1995.05.02 |
申请号 |
ZA19940008353 |
申请日期 |
1994.10.24 |
申请人 |
ASTRA AKTIEBOLAG. |
发明人 |
JOHN LESLIE EVENDEN;HANS SVERKER HANSSON;LARS GEORGE JOHANSSON;SVANTE BERTIL ROSS;SETH OLOV THORBERG;EVA MARIA HAMMARBERG;SVEN ERIK HELLBERG;JOHAN RUNE MICHAEL LUNDKVIST;DANIEL DUNGAN SOHN |
分类号 |
C07D311/58;A61K31/35;A61K31/352;A61K31/353;A61P9/12;A61P25/04;A61P25/06;A61P25/24;A61P25/26;A61P25/28;C07D335/06;C07D405/04;C07D405/12;C07D407/04;C07D409/04;C07D409/06;C07D409/12;C07D413/04;C07D413/06;C07D417/12 |
主分类号 |
C07D311/58 |
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
|