发明名称 |
Substituted urea and isothiourea derivatives as no synthase inhibitors |
摘要 |
The use of an N-substituted urea derivative for the manufacture of a medicament for the treatment of a condition where there is an advantage in inhibiting the NO synthase enzyme, in particular cerebral ischemia, and pharmaceutical formulations therefor are disclosed. Novel N-substituted urea derivatives and processes for the preparation thereof are also described. |
申请公布号 |
AU7705694(A) |
申请公布日期 |
1995.05.01 |
申请号 |
AU19940077056 |
申请日期 |
1994.10.03 |
申请人 |
THE WELLCOME FOUNDATION LIMITED |
发明人 |
JEFFREY ALAN OPLINGER;BARRY GEORGE SHEARER;ERIC CLEVELAND BIGHAM;ERIC STEVEN FURFINE;EDWARD PATRICK GARVEY |
分类号 |
C07D277/20;A61K31/00;A61K31/13;A61K31/135;A61K31/155;A61K31/16;A61K31/165;A61K31/195;A61K31/215;A61K31/425;A61K31/426;A61K31/44;A61P3/00;A61P9/00;A61P9/10;A61P25/28;A61P43/00;C07C275/16;C07C275/26;C07C275/28;C07C275/70;C07C281/06;C07C335/30;C07C335/32;C07D213/75;C07D277/18;C07D277/42 |
主分类号 |
C07D277/20 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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