发明名称 |
Boropeptide inhibitors of thrombin which contain a substituted pyrrolidine ring |
摘要 |
This invention relates to the discovery of novel and useful alpha -amino acid analogs, and the pharmaceutically acceptable salts and prodrugs thereof, containing a disubstituted pyrrolidine ring conjugated to an alpha -amino acid, useful as inhibitors of thrombin. |
申请公布号 |
AU7922794(A) |
申请公布日期 |
1995.05.01 |
申请号 |
AU19940079227 |
申请日期 |
1994.10.06 |
申请人 |
THE DU PONT MERCK PHARMACEUTICAL COMPANY |
发明人 |
GREGORY JAMES PACOFSKY;JAMES RUSSELL PRUITT;PATRICIA CAROL WEBER |
分类号 |
A61K38/00;C07D207/26;C07F5/02;C07F9/572;C07K5/06 |
主分类号 |
A61K38/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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