发明名称 METHOD OF MAKING CALCIFICATION-RESISTANT BIOPROSTHETIC TISSUE
摘要 <p>A method of treating a collagenous biomaterial, such as porcine aortic valve leaflets or bovine pericardium, by exposing the biomaterial to an alcohol to inhibit in vivo calcification. The biomaterial, preferably glutaraldehyde-pretreated, is subjected to an aqueous solution of 60 % to 80 % lower aliphatic alcohol, such as ethanol for a period of at least 20 minutes, and preferably, 24 to 72 hours. The biomaterial is rinsed, and then stored in either a glutaraldehyde-free environment or an ethanolic solution of glutaraldehyde.</p>
申请公布号 WO1995011047(A1) 申请公布日期 1995.04.27
申请号 US1994011937 申请日期 1994.10.20
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