发明名称 METHOD OF MAKING CALCIFICATION-RESISTANT BIOPROSTHETIC TISSUE
摘要 A method of treating a collagenous biomaterial, such as porcine aortic valve leaflets or bovine pericardium, by exposing the biomaterial to an alcohol to inhibit in vivo calcification. The biomaterial preferably glutaraldehyde-pretreated, is subjected to an aqueous solution of 60 % to 80 % lower aliphatic alcohol such as ethanol for a period of at least 20 minutes, and preferably, 24 to 72 hours. The biomaterial is rinsed, and then stored in either a glutaraldehyde-free environment or an ethanolic solution of glutaraldehyde.
申请公布号 CA2174665(A1) 申请公布日期 1995.04.27
申请号 CA19942174665 申请日期 1994.10.20
申请人 UNIVERSITY OF MICHIGAN 发明人 LEVY, ROBERT J.;HIRSCH, DANIELLE
分类号 A61L2/16;A61L27/00;A61L27/36;A61L27/50;A61L27/54;C14C3/00;C14C3/04 主分类号 A61L2/16
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