AZOOSPERMIA IDENTIFICATION AND TREATMENT

摘要

The present invention provides an AZF gene (seq ID Nos 1 & 2), and polynucleotide probes specifically binding to this gene or to naturally occurring variants thereof, as well as polypeptide probes specifically binding to the AZF polypeptide or to naturally occurring variants thereof. Expression of the gene in a host is also useful for providing means for use in the evaluation of drugs for use in increasing or decreasing expression of the AZF gene or AZF polypeptide.