| 摘要 |
<p>Nucleic acid able to cause specific cleavage of a bond between two ribonucleotides in an RNA-containing molecule. The RNA-containing molecule has the structure: 5'-XnUHZCUGANGAGYm-3', wherein each X and Y is independently any nucleotide base; n and m are independently between 5 and 40; H is U, A or C; Z is a hairpin loop, having between 6 and 60 bases, and each U, C, G and A is a uracil, cytosine, guanosine, or adenosine-containing ribonucleotide, respectively, and N is any ribonucleotide. The nucleic acid has the structure: 3'-X'nMoY'm-5', wherein each X' and Y' are complementary nucleotide bases to each corresponding X and Y, and Mo is a series of nucleotide bases active to cause the cleavage, and wherein Mo contains no ribonucletides.</p> |
