发明名称 DIHYDROBENZODIOXINYL PIPERAZINE DERIVATIVES AND PHARMACEUTICAL COMPOSITIONS
摘要 The present invention is concerned with compounds having 5-HT1A antagonistic activity useful in treating CNS disorders and having formula 2 <CHEM> wherein R1 is halogen, lower alkyl or alkoxy, hydroxy, trifluotomethyl or cyano, m has the value 1 or 2 and n has the value 0 or 1, A represents an alkylene chain containing 2-6 C-atoms which may be substituted with one or more lower alkyl groups or a monocyclic (hetero)aryl group, and B is methylene, ethylene, carbonyl, sulfinyl, sulfonyl or sulfur, and salts thereof.
申请公布号 NZ260891(A) 申请公布日期 1995.04.27
申请号 NZ19940260891 申请日期 1994.06.30
申请人 DUPHAR INTERNATIONAL RESEARCH BV 发明人 HARTOG, JAN;VAN STEEN, BARTHOLOMEUS JOHANNES;MOS, JOHANNES;SCHIPPER, JACQUES
分类号 C07D405/14;A61K31/495;A61P25/00;A61P25/18;A61P25/20;A61P25/24;A61P25/26;A61P25/28;A61P43/00;C07D209/00;C07D275/00;C07D295/00;C07D319/00;C07D405/12;C07D417/12;C07D417/14;(IPC1-7):C07D405/14 主分类号 C07D405/14
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