摘要 |
The present invention is concerned with compounds having 5-HT1A antagonistic activity useful in treating CNS disorders and having formula 2 <CHEM> wherein R1 is halogen, lower alkyl or alkoxy, hydroxy, trifluotomethyl or cyano, m has the value 1 or 2 and n has the value 0 or 1, A represents an alkylene chain containing 2-6 C-atoms which may be substituted with one or more lower alkyl groups or a monocyclic (hetero)aryl group, and B is methylene, ethylene, carbonyl, sulfinyl, sulfonyl or sulfur, and salts thereof. |