| 发明名称 |
16-SUBSTITUTED-4-AZA-ANDROSTANE 5-ALPHA-REDUCTASE ISOZYME 1 INHIBITORS |
| 摘要 |
Compounds of formula (I) are inhibitors of the 5.alpha.-reductase 1 isozyme, and are useful alone, or in combination with a 5.alpha.-reductase 2 inhibitor. for the treatment of androgenic sensitive disorders such as acne vulgaris, seborrhea, female hirsutism, male pattern baldness, and benign prostatic hyperplasia.
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| 申请公布号 |
CA2173863(A1) |
申请公布日期 |
1995.04.27 |
| 申请号 |
CA19942173863 |
申请日期 |
1994.10.21 |
| 申请人 |
MERCK & CO., INC. |
发明人 |
DURETTE, PHILIPPE L.;HAGMANN, WILLIAM K.;LANZA, THOMAS J., JR.;SAHOO, SOUMYA P.;RASMUSSON, GARY H.;TOLMAN, RICHARD L.;VON LANGEN, DEREK |
| 分类号 |
A61K31/58;A61P5/24;A61P17/14;A61P29/00;C07J73/00;(IPC1-7):C07J73/00 |
主分类号 |
A61K31/58 |
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