USE OF 2-(2-ALKYLPHENYLAMINO)-OXAZOLINES, -THIAZOLINES AND -IMIDAZOLINES AS ALPHA 2 ADRENERGIC AGENTS

摘要

A pharmaceutical composition, useful for treating animals of the mammalian species, including humans, to treat diseases and conditions which normally respond to treatment with alpha2 adrenergic agents, contains as its active alpha2 adrenergic agent ingredient one or more compounds of formula (I) where X is O, S or NH; n is an integer with the values of 0, 1 or 2; when n is 0 then R1 is lower alkyl having 1 to 6 carbon atoms and R2 is H or lower alkyl having 1 to 6 carbon atoms; when n is 1 or 2, then R1 and R2 both are methylene (CH2), or methylene substituted with an R5 group where R5 is lower alkyl of 1 to 6 carbons; R3 and R4 independently are H or lower alkyl having 1 to 6 carbons; R6 is H or lower alkyl of 1 to 6 carbons.