| 发明名称 |
NUCLEOTIDE VECTOR, COMPOSITION CONTAINING SUCH VECTOR AND VACCINE FOR IMMUNIZATION AGAINST HEPATITIS |
| 摘要 |
<p>Nucleotide vector comprising at least one gene or one complementary DNA coding for at least a portion of a protein of a virus, and a promoter providing for the expression of such gene in muscle cells. The gene may be the S gene of the hepatitis B virus. A vaccine preparation containing said bare DNA is injected into the host previously treated with a substance capable of inducing a coagulating necrosis of the muscle fibers.</p> |
| 申请公布号 |
CA2174652(A1) |
申请公布日期 |
1995.04.27 |
| 申请号 |
CA19942174652 |
申请日期 |
1994.04.27 |
| 申请人 |
INSTITUT PASTEUR;INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (INSERM);UNIVERSITE D'OTTAWA |
发明人 |
DAVIS, HEATHER LYNN;WHALEN, ROBERT GERARD;MICHEL, MARIE-LOUISE |
| 分类号 |
A61K39/00;A61K39/29;A61K48/00;C07K14/02;(IPC1-7):C12N15/85;C12N15/51;A61K31/70;A61K39/12 |
主分类号 |
A61K39/00 |
| 代理机构 |
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代理人 |
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