发明名称 Stereoselective reduction of ketones.
摘要 The present invention concerns a process for the stereoselective enzymatic reduction of keto group-containing compounds such as N-(4-(2-chloroacetyl)phenyl)methanesulfonamido to form the corresponding hydroxyl-group containing compound. The process is selective for the D(+) enantiomer and is catalyzed by enzymes such as oxido-reductase or dehydrogense, or by microorganisms such as Hansenula, Rhodococcus, or Norcardia species.
申请公布号 EP0596490(A3) 申请公布日期 1995.04.26
申请号 EP19930117899 申请日期 1993.11.04
申请人 SQUIBB BRISTOL MYERS CO 发明人 PATEL RAMESH N;BANERJEE AMIT;MCNAMEE CLYDE G;SZARKA LASZLO J
分类号 A61K31/18;A61P9/00;C07C311/08;C07C311/21;C12P13/02;C12P41/00;C12R1/01;C12R1/645 主分类号 A61K31/18
代理机构 代理人
主权项
地址