| 发明名称 |
METHODS AND COMPOSITIONS OF A BIOARTIFICIAL KIDNEY SUITABLE FOR USE IN VIVO OR EX VIVO |
| 摘要 |
A novel cell seeded hollow fiber bioreactor is described as a potential bioartifical kidney. Renal cells are seeded along a hollow fiber (10) in a perfused bioreactor to reproduce the ultrafiltration function and transport function of the kidney. Maintenance of tissue specific function and ultrastructure suggest that this bioreactor provides an economical device for treating renal failure as well as studying renal tubululogenesis in vitro.
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| 申请公布号 |
CA2173594(A1) |
申请公布日期 |
1995.04.27 |
| 申请号 |
CA19942173594 |
申请日期 |
1994.10.11 |
| 申请人 |
REGENTS OF THE UNIVERSITY OF MICHIGAN (THE) |
发明人 |
HUMES, H. DAVID;CIESLINSKI, DEBORAH A. |
| 分类号 |
C12N15/09;A61F2/02;A61K31/20;A61K31/557;A61K31/57;A61K33/12;A61K33/24;A61K35/12;A61K38/22;A61K48/00;A61L27/00;A61M1/14;A61M1/18;A61P13/02;A61P15/00;C12M3/06;C12N5/00;C12N5/02;C12N5/071;C12N5/074;C12N5/10;C12N15/63;C12N15/85;(IPC1-7):A61M1/14 |
主分类号 |
C12N15/09 |
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