摘要 |
An antibacterial 7beta-(carboxyalkenoyl)amino-3-cephem-4-carboxylic acid represented by the following formula: <IMAGE> (wherein R is aryl or a heterocyclic group; R1 is hydrogen or halogen; R2 is a single bond, alkylene, or thiaalkylene; R3 is a hydrogen atom or carboxy modifying group; R4 is hydrogen or methoxy; R5 is hydrogen or a 3-substituent of cephalosporins; R6 is a hydrogen atom or carboxy modifying group; and X is oxygen, sulfur, or sulfinyl) a pharmaceutical composition containing the same, and a method for treating a bacterial infection with the same. |