发明名称 |
Enzymatic hydroxylation process for the preparation of HMG-COA reductase inhibitors and intermediates thereof. |
摘要 |
<p>An enzymatic hydroxylation process for the preparation of compounds useful as HMG-CoA reductase inhibitors and/or as intermediates in the preparation of HMG-CoA reductase inhibitors uses a microorganism or an enzyme derived from, or having the structure of an enzyme derived from, said microorganism, which is capable of catalyzing the hydroxylation process.</p> |
申请公布号 |
EP0649907(A1) |
申请公布日期 |
1995.04.26 |
申请号 |
EP19940116409 |
申请日期 |
1994.10.18 |
申请人 |
BRISTOL-MYERS SQUIBB COMPANY |
发明人 |
DAVIS, BRIAN L.;CINO, PAUL M.;SZARKA, LASZLO |
分类号 |
C12P7/40;A61K31/215;A61P3/06;C12P7/02;C12P7/62;C12P17/06;C12R1/01;C12R1/465;C12R1/645;(IPC1-7):C12P7/02;A61K31/045;A61K31/365;A61K31/35 |
主分类号 |
C12P7/40 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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