发明名称 |
MONOCLONAL ANTIBODY FOR COLORECTAL CARCINOMA |
摘要 |
A monoclonal antibody raised to colorectal carcinoma, and a hybridoma which elicits the antibody, have been produced. This antibody, ND4 has been discovered to react with a new tumor marker, a glycoprotein of approximately 160 kD found on the surface of undifferentiated colorectal carcinoma cells; it does not cross-react with other known tumor markers. It is useful for detecting and monitoring colorectal carcinoma.
|
申请公布号 |
CA1335353(C) |
申请公布日期 |
1995.04.25 |
申请号 |
CA19890597146 |
申请日期 |
1989.04.19 |
申请人 |
NEW ENGLAND DEACONESS HOSPITAL CORPORATION;MALLORY INSTITUTE OF PATHOLOGY FOUNDATION |
发明人 |
SALEM, RONALD R.;THOMAS, PETER;STEELE, GLENN;ZAMCHECK, NORMAN |
分类号 |
C07K16/30;C12N15/12;(IPC1-7):C12P21/08;C12N5/18;G01N33/574;G01N33/577 |
主分类号 |
C07K16/30 |
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
|