| 发明名称 |
THERAPEUTIC USES OF 2',5'-OLIGOADENYLATES |
| 摘要 |
Synthetic analogs of 2',5'-oligoadenylate (2-5A) wherein the aglycon, ribosyl moiety and/or terminal nucleoside have been modified are effective therapeutic agents, particularly against HIV infection. The analogs are utilized in compositions and methods for the treatment of disorders characterized by 2-5A pathway defects.
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| 申请公布号 |
CA1335356(C) |
申请公布日期 |
1995.04.25 |
| 申请号 |
CA19890602302 |
申请日期 |
1989.06.09 |
| 申请人 |
TEMPLE UNIVERSITY - OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION |
发明人 |
SUHADOLNIK, ROBERT J.;PFLEIDERER, WOLFGANG |
| 分类号 |
C07H19/16;A61K31/00;A61K31/70;A61K31/7042;A61K31/7052;A61K31/7076;A61K31/7088;A61P31/00;A61P31/12;C07H21/00;C07H23/00;(IPC1-7):A61K31/70 |
主分类号 |
C07H19/16 |
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