发明名称 [(alkoxy)pyridinyl]amine compounds which are useful in the treatment of gastrointestinal disorders
摘要 PCT No. PCT/EP93/00174 Sec. 371 Date Jul. 20, 1994 Sec. 102(e) Date Jul. 20, 1994 PCT Filed Jan. 26, 1993 PCT Pub. No. WO93/15055 PCT Pub. Date Aug. 5, 1993.The present invention relates to N-pyridylamidine and N-pyridylguanidine derivatives of general formula (I) in which: Ar1 is an optionally substituted phenyl ring; Ar2 is an optionally substituted phenyl ring; R1 is hydrogen or C1-4alkyl; R2 is hydrogen or C1-4alkyl; R3 is hydrogen or C1-4alkyl; R4 is hydrogen, halogen, C1-6alkyl or C1-6alkoxy; X is CH2 or NR5, and R5 is hydrogen or C1-4alkyl, and the salts thereof, and their use in therapy as gastric acid secretion inhibitors.
申请公布号 US5409943(A) 申请公布日期 1995.04.25
申请号 US19940256697 申请日期 1994.07.20
申请人 SMITHKLINE BEECHAM INTERCREDIT B.V. 发明人 IFE, ROBERT J.;LEACH, COLIN A.;DHANAK, DASHYANT
分类号 A61K31/44;A61K31/4418;A61P1/04;C07D213/75;(IPC1-7):C07D213/75 主分类号 A61K31/44
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