A controlled release device for delivering a liquid substance to a patient at a predetermined time following administration comprises a male hydrogel plug (2) engaged in the neck (4) of a female body (6). The liquid substance (12) is contained within a container (10) formed of a water-soluble material retained within the device, thereby preventing interference or interaction of the liquid with the remainder of the device. When the device is placed in an aqueous environment (e.g., the gastrointestinal tract) the hydrogel plug swells and disengages after a predetermined time, exposing the water-soluble container to the aqueous environment, and dissolution thereof to release the liquid.
申请公布号
WO9510262(A1)
申请公布日期
1995.04.20
申请号
WO1994GB02205
申请日期
1994.10.10
申请人
R.P. SCHERER CORPORATION;STEVENS, HOWARD, NORMAN, ERNEST;BINNS, JULIE, STEPHANIE;WADDINGTON, DAVID
发明人
STEVENS, HOWARD, NORMAN, ERNEST;BINNS, JULIE, STEPHANIE;WADDINGTON, DAVID