摘要 |
The present invention provides novel compounds, compounds and pharmaceutical compositions thereof, and methods of using same in the treatment of affective disorders, anxiety, depression, post-traumatic stress disorders, eating disorders, supranuclear palsy, irritable bowel syndrome, immune suppression, Alzheimer's disease, gastrointestinal diseases, anorexia nervosa, drug and alcohol withdrawal symptoms, drug addiction, inflammatory disorders, or fertility problems. The novel compounds provided by this invention are those of formula (I), wherein R1, R3, R4, R5, Z, Y, V, X, X', J, K, L, and M are as defined herein.
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申请人 |
DUPONT MERCK PHARMACEUTICAL COMPANY (THE) |
发明人 |
ALDRICH, PAUL EDWARD;ARVANITIS, ARGYRIOS GEORGIOS;CHEESEMAN, ROBERT SCOTT;CHORVAT, ROBERT JOHN;CHRISTOS, THOMAS EUGENE;GILLIGAN, PAUL JOSEPH;GRIGORIADIS, DIMITRI EMIL;HODGE, CARL NICHOLAS;KRENITSKY, PAUL JOHN;SCHOLFIELD, EVERETT LATHAM;TAM, SANG WILLIAM;WASSERMAN, ZELDA RAKOWITZ |