| 摘要 |
<p>The invention involves the cross-linking of presented peptides to their corresponding MHC molecule or a soluble MHC derivative which has similar antigen binding properties, to form covalent complexes of the two molecules. The resulting materials are useful in provoking an immune response as well as in the identification of cytolytic T lymphocytes specific for the peptide of interest. The peptides are cross-linked to their partner molecule via a photoactivatable material which is attached to the peptide. Upon exposure to light at an appropriate frequency, the peptide cross-links to the MHC molecule.</p> |
