发明名称 N-(3-(3-(1-PIPERIDINYLMETHYL)PHENOXY)PROPYL) HYDROXYACETAMIDE-2-HYDROXY-1,2,3-PROPENETRICARBOXYLATE BISMUTH (3+) COMPLEX AND THE METHOD FOR PREPARATION
摘要 <p>The N-(3-(3-(1-piperidinylmethyl)phenoxy)propyl) hydroxyacetamide-2-hydroxy-1,2,3-propenetricarboxylate bismuth (3+) complex (1:1:1) with formula (II) is obtained as a result of the interaction between N-(3-(3-(1-piperidinylmethyl)phenoxy)propyl) hydroxyacetamide and bismuth citrate in a boiling water. The bismuth salt (II) possesses a high antisecretory and cytoprotective activity, as well as an antibacterial effect against Helicobacter pylori, and is used in tablet form or as capsules for the treatment of gastric and duodenal ulcers.</p>
申请公布号 WO1995009162(A1) 申请公布日期 1995.04.06
申请号 BG1994000009 申请日期 1994.07.28
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