| 摘要 |
A chemotactic factor released from tissue in response to injury represents the initial signal that recruits neutrophils to the tissue. As released, the factor exists as a positively charged protein complex consisting of a low molecular weight active peptide factor that carries a neutral to negative charge and a weakly associated high molecular weight protein. The tissue derived complex exhibits a molecular weight of about 100,000-300,000 daltons and the factor is obtained therefrom and purified. The peptide factor is non-immune cell derived and non-serum derived and exhibits a molecular weight of approximately 3,000 daltons.
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