| 摘要 |
<p>The present invention relates to a non-competitive immunoassay for detecting the presence of an unknown analyte in solution. It comprises: a) an ion channel receptor immobilized in a lipid film which is in contact with an ion-containing solution on each side thereof; b) a ligand, conjugated to the receptor, which has particular affinity for the analyte in solution, and, which, upon binding to the analyte in solution, causes an inhibition in ion flow through the channel; and c) means to detect the inhibition of ion flow through the channel in response to the binding of conjugated ligand and analyte.</p> |
