| 摘要 |
<p>The present invention provides novel hybridoma cell lines which produce novel monoclonal antibodies (MoAbs) which specifically bind epitopes found on a structural protein of feline infectious peritonitis virus (FIPV), exhibit no cross-reactivity with relates coronaviruses, and fail to induce antibody-dependent enhancement of infection. The novel MoAbs produced by the hybridoma cell lines of the invention can be use in assays for the detection of feline infectious peritonitis virus in domestic as well as exotic cats, and for the therapeutic and/or prophylactic treatment of cats against feline infectious peritonitis (FIP) from infection by FIPV.</p> |
