摘要 |
<p>A prolonged releasing pharmaceutical preparation is provided carrying a physiologically active substance, particularly, calcitonin gene-related peptide (CGRP) or a maxadilan (MAX). This pharmaceutical preparation can attain the expected effects by incorpolating the physiologically active substance into a combination, as carriers for the physiologically active substance, of a cellulosic polymer and at least one auxiliary component selected from the group consisting of fats and oils, waxes, fatty acids, saccharides and polyacrylate ester derivatives. The pharmaceutical preparation can conveniently be used, in living bodies, particularly as an intrathecal implantation-type preparation.</p> |
申请人 |
SHISEIDO COMPANY LIMITED |
发明人 |
TAJIMA, MASAHIRO, C/O SHISEIDO RESEARCH CENTER;YOSHIMOTO, TAKASHI, C/O TOHOKU UNIVERSITY;FUKUSHIMA, SHOJI, C/O SHISEIDO RESEARCH CENTER;KAMINUMA, TOSHIHIKO, C/O SHISEIDO RESEARCH CENTER;EHAMA, RITSUKO, C/O SHISEIDO COMPANY, LTD.;BABA, TAKAAKI, C/O SHISEIDO RESEARCH CENTER;WATABE, KAZUO, C/O SHISEIDO RESEARCH CENTER |