发明名称 |
ANTIBACTERIAL COMPOSITION FOR ORAL ADMINISTRATION |
摘要 |
An antibacterial composition for oral administration comprising pivaloyloxymethyl-(6R,7R)-7¢(Z)-2-(2-aminothiazol-4-yl)-2-methoxyiminoacetamide!-3-¢(Z)-2- (4-methylthiazol-5-yl)-ethenyl!cephem-4-carboxylate, .beta.cyclodextrin and a pharmaceutically acceptable carrier is disclosed. The addition of .beta.-cyclodextrin remarkably improves the dispersibility of the substance ME1207 to thereby promote the absorption of the same. Thus, the absorbability of the substance ME1207 administered at a hungry state is elevated to a level comparable to that achieved by administering the same after meals.
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申请公布号 |
CA1334934(C) |
申请公布日期 |
1995.03.28 |
申请号 |
CA19890597069 |
申请日期 |
1989.04.18 |
申请人 |
MEIJI SEIKA KAISHA, LTD. |
发明人 |
KIKKOJI, TOSHIHIRO;KOBAYASHI, TOSHIYUKI;SATO, TOYOMI;WATANABE, KOJI;NISHIZAWA, KENJI |
分类号 |
A61K9/20;A61K31/545;A61K31/546;A61K47/00;A61K47/34;A61K47/40;A61P31/04;C07D501/22;C08B37/00;(IPC1-7):A61K31/545;A61K31/715 |
主分类号 |
A61K9/20 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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