发明名称 ANTIBACTERIAL COMPOSITION FOR ORAL ADMINISTRATION
摘要 An antibacterial composition for oral administration comprising pivaloyloxymethyl-(6R,7R)-7¢(Z)-2-(2-aminothiazol-4-yl)-2-methoxyiminoacetamide!-3-¢(Z)-2- (4-methylthiazol-5-yl)-ethenyl!cephem-4-carboxylate, .beta.cyclodextrin and a pharmaceutically acceptable carrier is disclosed. The addition of .beta.-cyclodextrin remarkably improves the dispersibility of the substance ME1207 to thereby promote the absorption of the same. Thus, the absorbability of the substance ME1207 administered at a hungry state is elevated to a level comparable to that achieved by administering the same after meals.
申请公布号 CA1334934(C) 申请公布日期 1995.03.28
申请号 CA19890597069 申请日期 1989.04.18
申请人 MEIJI SEIKA KAISHA, LTD. 发明人 KIKKOJI, TOSHIHIRO;KOBAYASHI, TOSHIYUKI;SATO, TOYOMI;WATANABE, KOJI;NISHIZAWA, KENJI
分类号 A61K9/20;A61K31/545;A61K31/546;A61K47/00;A61K47/34;A61K47/40;A61P31/04;C07D501/22;C08B37/00;(IPC1-7):A61K31/545;A61K31/715 主分类号 A61K9/20
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