发明名称 POLYAZAMACROCYCLIC COMPOUNDS FOR COMPLEXATION OF METAL IONS
摘要 A nuclear magnetic resonance contrast composition which comprises a tetraazamacrocyclic compound - paramagnetic lanthanide complex having the formula: <CHEM> where x is 2, 3 or a combination of p 2(s) and q 3(s) where p + q = 4; R is (CH2)zP(=O)OR<1>OR<2>; R<1> is H or CH3; R<2> is CnH1+2n; z is 1 to 3; r is 2 or 3; M is a paramagnetic lanthanide; and n is 4 to 6. The nuclear magnetic resonance contrast compositions are particularly suitable for liver imaging in a subject.
申请公布号 HU9500283(D0) 申请公布日期 1995.03.28
申请号 HU19950000283 申请日期 1993.06.28
申请人 BOARD OF REGENTS THE UNIVERSITY OF TEXAS SYSTEM;THE DOW CHEMICAL CO. 发明人 KIEFER,GARRY E.;SHERRY,ALLAN DEAN
分类号 A61K49/00;A61K49/04;A61K49/06;A61K51/00;A61K51/04;C07D255/02;C07D257/02;C07D259/00;C07F;C07F9/6515;C07F9/6524;C08G59/70 主分类号 A61K49/00
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