2'methylidenepyrimidine nucleoside compounds, their use and method for production thereof

摘要

2'-Methylidenepyrimidine nucleoside compounds of the general formula: <IMAGE> wherein R1 stands for amino or hydroxy group; R2 stands for a halogen or a lower alkyl when R1 is amino or R2 stands for an alkyl having 2 to 4 carbon atoms, an alkynyl having 2 to 4 carbon atoms or a haloalkyl when R1 is hydroxy group; and R3 stands for hydrogen or a phosphoric acid residue, or salts thereof, compositions containing one or more of these compounds and methods for production of these compounds are disclosed. Said compounds and salts thereof exhibit noticeable antitumor activities.