发明名称 |
Derivatives of substituted imidazol-2-one and process for their preparation |
摘要 |
Derivatives of 1-phenyl-3-azabicycloalkylimidazolidin-2-ones are provided of general formula (I) <IMAGE> (I) in which inter alia R3 represents a group <IMAGE> wherein n is an integer of 1 or 2 and R8 is hydrogen, C1-C6 alkyl unsubstituted or substituted by phenyl, C2-C4 alkenyl, C2-C4 alkynyl, formyl or C2-C6 alkanoyl; and the pharmaceutically acceptable salts thereof, which are useful in the treatment of CNS disorders, gut motility disorders, emesis and migraine, as cognition activators, anti-drug addition agents and analgesic.
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申请公布号 |
US5401750(A) |
申请公布日期 |
1995.03.28 |
申请号 |
US19930076153 |
申请日期 |
1993.06.14 |
申请人 |
FARMITALIA CARLO ERBA S.R.L. |
发明人 |
VARASI, MARIO;HEIDEMPERGHER, FRANCO;CARFAGNA, NICOLA;FARIELLO, RUGGERO |
分类号 |
A61K31/435;A61K31/4166;A61K31/429;A61P1/00;A61P1/08;A61P25/00;A61P25/04;A61P25/06;A61P25/28;A61P25/30;A61P29/00;A61P43/00;C07D233/32;C07D403/04;C07D451/02;C07D451/04;C07D451/14;C07D453/02;(IPC1-7):C07D401/04;A61K31/46 |
主分类号 |
A61K31/435 |
代理机构 |
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代理人 |
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地址 |
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