摘要 |
<p>A device for administering a drug at a controlled rate for a prolonged period of time comprising, a solid inner matric material having solid particles of the drug dispersed therethrough, the inner matrix being permeable to passage of the drug by diffusion and a polymeric membrane, insoluble in body fluids, surrounding the inner matrix, the polymeric membrane being permeable to passage of the drug by diffusion but at a lower rate than through the inner matrix, whereby the drug will diffuse through the inner matrix to and through the polymeric membrane at a controlled rate for a prolonged period of time.</p> |